Discontinuation of fucose therapy in LADII causes rapid loss of selectin ligands and rise of leukocyte counts.

Leukocyte adhesion deficiency type II (LADII) is a rare inherited disorder of fucose metabolism. Patients with LADII lack fucosylated glycoconjugates, including the carbohydrate ligands of the selectins, leading to an immunodeficiency caused by the lack of selectin-mediated leukocyte-endothelial int...

詳細記述

書誌詳細
主要な著者: Lühn, K, Marquardt, T, Harms, E, Vestweber, D
フォーマット: Journal article
言語:English
出版事項: 2001