MEK inhibitors block growth of lung tumors with mutations in Ataxia Telangiectasia Mutated
Lung cancer is the leading cause of cancer deaths, and effective treatments are urgently needed. Loss-of-function mutations in the DNA damage response kinase ATM are common in lung adenocarcinoma but directly targeting these with drugs remains challenging. Here we report that ATM loss-of-function is...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Izdano: |
Nature Publishing Group
2016
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