IL-15 reprogramming compensates for NK cell mitochondrial dysfunction in HIV-1 infection

Dynamic regulation of cellular metabolism is important for maintaining homeostasis and can directly influence immune cell function and differentiation, including NK cell responses. Persistent HIV-1 infection leads to a state of chronic immune activation, NK cell subset redistribution, and progressiv...

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Main Authors: Moreno-Cubero, E, Alrubayyi, A, Balint, S, Ogbe, A, Rowland-Jones, SL, Borrow, P, Dustin, M
格式: Journal article
语言:English
出版: American Society for Clinical Investigation 2024