Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling.

Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling.

The stimulation of Toll-like receptors (TLRs) on macrophages by pathogen-associated molecular patterns (PAMPs) results in the activation of intracellular signaling pathways that are required for initiating a host immune response. Both phosphatidylinositol 3-kinase (PI3K)-Akt and p38 mitogen-activate...

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Dettagli Bibliografici
Autori principali:	McGuire, V, Gray, A, Monk, C, Santos, S, Lee, K, Aubareda, A, Crowe, J, Ronkina, N, Schwermann, J, Batty, I, Leslie, N, Dean, J, O'Keefe, S, Boothby, M, Gaestel, M, Arthur, J
Natura:	Journal article
Lingua:	English
Pubblicazione:	2013

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