Proton beam therapy – the challenges of delivering high-quality evidence of clinical benefit
The use of proton beam therapy (PBT) offers the opportunity to improve greater conformality of radiotherapy treatment delivery in some patients. However, it is associated with a high capital cost and the need to build new dedicated facilities. We discuss how the global radiotherapy community can res...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Elsevier
2018
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| _version_ | 1826303087082471424 |
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| author | National Cancer Research Institute Clinical and Translational Radiotherapy Research Working Group (CTRad) Proton Beam Clinical Trial Strategy Group Amos, R Bulbeck, H Burnet, N Crellin, A Eaton, D Evans, P Hall, E Hawkins, M Kirby, K Mackay, R Sebag-Montefiore, D Sharma, R |
| author_facet | National Cancer Research Institute Clinical and Translational Radiotherapy Research Working Group (CTRad) Proton Beam Clinical Trial Strategy Group Amos, R Bulbeck, H Burnet, N Crellin, A Eaton, D Evans, P Hall, E Hawkins, M Kirby, K Mackay, R Sebag-Montefiore, D Sharma, R |
| author_sort | National Cancer Research Institute Clinical and Translational Radiotherapy Research Working Group |
| collection | OXFORD |
| description | The use of proton beam therapy (PBT) offers the opportunity to improve greater conformality of radiotherapy treatment delivery in some patients. However, it is associated with a high capital cost and the need to build new dedicated facilities. We discuss how the global radiotherapy community can respond to the challenge of producing high-quality evidence of clinical benefit from PBT in adult patients. In the UK, the National Cancer Research Institute-funded Clinical and Radiotherapy Translational group has established the PBT Clinical Trial Strategy Group. An eight-point framework is described that can assist the development and delivery of high-quality clinical trials. |
| first_indexed | 2024-03-07T05:57:18Z |
| format | Journal article |
| id | oxford-uuid:eaf77f7f-29aa-4a55-884f-1b1d39ee7a5e |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:57:18Z |
| publishDate | 2018 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:eaf77f7f-29aa-4a55-884f-1b1d39ee7a5e2022-03-27T11:06:09ZProton beam therapy – the challenges of delivering high-quality evidence of clinical benefitJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:eaf77f7f-29aa-4a55-884f-1b1d39ee7a5eEnglishSymplectic Elements at OxfordElsevier2018National Cancer Research Institute Clinical and Translational Radiotherapy Research Working Group(CTRad) Proton Beam Clinical Trial Strategy GroupAmos, RBulbeck, HBurnet, NCrellin, AEaton, DEvans, PHall, EHawkins, MKirby, KMackay, RSebag-Montefiore, DSharma, RThe use of proton beam therapy (PBT) offers the opportunity to improve greater conformality of radiotherapy treatment delivery in some patients. However, it is associated with a high capital cost and the need to build new dedicated facilities. We discuss how the global radiotherapy community can respond to the challenge of producing high-quality evidence of clinical benefit from PBT in adult patients. In the UK, the National Cancer Research Institute-funded Clinical and Radiotherapy Translational group has established the PBT Clinical Trial Strategy Group. An eight-point framework is described that can assist the development and delivery of high-quality clinical trials. |
| spellingShingle | National Cancer Research Institute Clinical and Translational Radiotherapy Research Working Group (CTRad) Proton Beam Clinical Trial Strategy Group Amos, R Bulbeck, H Burnet, N Crellin, A Eaton, D Evans, P Hall, E Hawkins, M Kirby, K Mackay, R Sebag-Montefiore, D Sharma, R Proton beam therapy – the challenges of delivering high-quality evidence of clinical benefit |
| title | Proton beam therapy – the challenges of delivering high-quality evidence of clinical benefit |
| title_full | Proton beam therapy – the challenges of delivering high-quality evidence of clinical benefit |
| title_fullStr | Proton beam therapy – the challenges of delivering high-quality evidence of clinical benefit |
| title_full_unstemmed | Proton beam therapy – the challenges of delivering high-quality evidence of clinical benefit |
| title_short | Proton beam therapy – the challenges of delivering high-quality evidence of clinical benefit |
| title_sort | proton beam therapy the challenges of delivering high quality evidence of clinical benefit |
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