The role of elements binding CTCF and cohesin in directing tissue-specific enhancer activity
<p>Distal enhancer elements regulate the tissue-specific expression of their target genes via the establishment of physical interactions with the gene promoter. In mice, a cluster of five enhancers, jointly classified as a super-enhancer, specifically upregulate <em>α</em>-globin g...
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| Format: | Thesis |
| Language: | English |
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2016
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