Functionalised pyrrolidinones by conjugate addition of stabilised enolates and reformatsky reagents
The α,β-unsaturated lactam 1b has been found to readily undergo conjugate addition reactions with a range of stabilised carbon nucleophiles and Reformatsky reagents under mild conditions in good yield with high diastereoselectivity. This method provides a simple and versatile approach to highly func...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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1996
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| _version_ | 1797101848796069888 |
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| author | Dyer, J Keeling, S Moloney, M |
| author_facet | Dyer, J Keeling, S Moloney, M |
| author_sort | Dyer, J |
| collection | OXFORD |
| description | The α,β-unsaturated lactam 1b has been found to readily undergo conjugate addition reactions with a range of stabilised carbon nucleophiles and Reformatsky reagents under mild conditions in good yield with high diastereoselectivity. This method provides a simple and versatile approach to highly functionalised pyrrolidinones. |
| first_indexed | 2024-03-07T05:57:42Z |
| format | Journal article |
| id | oxford-uuid:eb19541f-c78f-475d-a264-eae3778bf29f |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:57:42Z |
| publishDate | 1996 |
| record_format | dspace |
| spelling | oxford-uuid:eb19541f-c78f-475d-a264-eae3778bf29f2022-03-27T11:07:08ZFunctionalised pyrrolidinones by conjugate addition of stabilised enolates and reformatsky reagentsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:eb19541f-c78f-475d-a264-eae3778bf29fEnglishSymplectic Elements at Oxford1996Dyer, JKeeling, SMoloney, MThe α,β-unsaturated lactam 1b has been found to readily undergo conjugate addition reactions with a range of stabilised carbon nucleophiles and Reformatsky reagents under mild conditions in good yield with high diastereoselectivity. This method provides a simple and versatile approach to highly functionalised pyrrolidinones. |
| spellingShingle | Dyer, J Keeling, S Moloney, M Functionalised pyrrolidinones by conjugate addition of stabilised enolates and reformatsky reagents |
| title | Functionalised pyrrolidinones by conjugate addition of stabilised enolates and reformatsky reagents |
| title_full | Functionalised pyrrolidinones by conjugate addition of stabilised enolates and reformatsky reagents |
| title_fullStr | Functionalised pyrrolidinones by conjugate addition of stabilised enolates and reformatsky reagents |
| title_full_unstemmed | Functionalised pyrrolidinones by conjugate addition of stabilised enolates and reformatsky reagents |
| title_short | Functionalised pyrrolidinones by conjugate addition of stabilised enolates and reformatsky reagents |
| title_sort | functionalised pyrrolidinones by conjugate addition of stabilised enolates and reformatsky reagents |
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