Functionalised pyrrolidinones by conjugate addition of stabilised enolates and reformatsky reagents
The α,β-unsaturated lactam 1b has been found to readily undergo conjugate addition reactions with a range of stabilised carbon nucleophiles and Reformatsky reagents under mild conditions in good yield with high diastereoselectivity. This method provides a simple and versatile approach to highly func...
Main Authors: | Dyer, J, Keeling, S, Moloney, M |
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Format: | Journal article |
Language: | English |
Published: |
1996
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