Modulating the immune system by amino acid depletion - IDO and beyond
<p>Amino acid availability plays an important role in modulating the activity of T-cells. One of the pathways employed by T-cells to sense nutrient levels is the “mammalian target of rapamycin” (mTOR) pathway that is inhibited in response to nutrient depletion. Indoleamine 2,3-dioxygenase (IDO...
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| Médium: | Diplomová práce |
| Jazyk: | English |
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2011
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