Depletion effects and loop formation in self-avoiding polymers.
Langevin dynamics is employed to study the looping kinetics of self-avoiding polymers both in ideal and crowded solutions. A rich kinetics results from the competition of two crowding-induced effects: the depletion attraction and the enhanced viscous friction. For short chains, the enhanced friction...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2006
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| _version_ | 1797101876013957120 |
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| author | Toan, N Marenduzzo, D Cook, P Micheletti, C |
| author_facet | Toan, N Marenduzzo, D Cook, P Micheletti, C |
| author_sort | Toan, N |
| collection | OXFORD |
| description | Langevin dynamics is employed to study the looping kinetics of self-avoiding polymers both in ideal and crowded solutions. A rich kinetics results from the competition of two crowding-induced effects: the depletion attraction and the enhanced viscous friction. For short chains, the enhanced friction slows down looping, while for longer chains, the depletion attraction renders it more frequent and persistent. We discuss the possible relevance of the findings for chromatin looping in living cells. |
| first_indexed | 2024-03-07T05:58:08Z |
| format | Journal article |
| id | oxford-uuid:eb3b0e45-39d3-4baa-829b-d8231272fddf |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:58:08Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | oxford-uuid:eb3b0e45-39d3-4baa-829b-d8231272fddf2022-03-27T11:08:06ZDepletion effects and loop formation in self-avoiding polymers.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:eb3b0e45-39d3-4baa-829b-d8231272fddfEnglishSymplectic Elements at Oxford2006Toan, NMarenduzzo, DCook, PMicheletti, CLangevin dynamics is employed to study the looping kinetics of self-avoiding polymers both in ideal and crowded solutions. A rich kinetics results from the competition of two crowding-induced effects: the depletion attraction and the enhanced viscous friction. For short chains, the enhanced friction slows down looping, while for longer chains, the depletion attraction renders it more frequent and persistent. We discuss the possible relevance of the findings for chromatin looping in living cells. |
| spellingShingle | Toan, N Marenduzzo, D Cook, P Micheletti, C Depletion effects and loop formation in self-avoiding polymers. |
| title | Depletion effects and loop formation in self-avoiding polymers. |
| title_full | Depletion effects and loop formation in self-avoiding polymers. |
| title_fullStr | Depletion effects and loop formation in self-avoiding polymers. |
| title_full_unstemmed | Depletion effects and loop formation in self-avoiding polymers. |
| title_short | Depletion effects and loop formation in self-avoiding polymers. |
| title_sort | depletion effects and loop formation in self avoiding polymers |
| work_keys_str_mv | AT toann depletioneffectsandloopformationinselfavoidingpolymers AT marenduzzod depletioneffectsandloopformationinselfavoidingpolymers AT cookp depletioneffectsandloopformationinselfavoidingpolymers AT michelettic depletioneffectsandloopformationinselfavoidingpolymers |