Investigating isocitrate dehydrogenase mutations in cancer using new metabolomics methods
<p>Altered cellular metabolism, as a result of oncogenic mutations, has been observed in a range of cancer types. A detailed understanding of how cancers modify cellular metabolism, which includes changes to the genome, proteome and metabolome, is therefore integral for the development of effe...
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Format: | Thesis |
Language: | English |
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2020
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