Investigating isocitrate dehydrogenase mutations in cancer using new metabolomics methods

<p>Altered cellular metabolism, as a result of oncogenic mutations, has been observed in a range of cancer types. A detailed understanding of how cancers modify cellular metabolism, which includes changes to the genome, proteome and metabolome, is therefore integral for the development of effe...

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Bibliographic Details
Main Author: Walsby-Tickle, J
Other Authors: McCullagh, J
Format: Thesis
Language:English
Published: 2020
Subjects: