Increasing the survival of dendritic cells in vivo does not replace the requirement for CD4+ T cell help during primary CD8+ T cell responses.

The survival of dendritic cells (DC) in vivo determines the duration of Ag presentation and is critical in determining the strength and magnitude of the resulting T cell response. We used a mouse model to show that Ag-loaded C57BL/6 DC (MHC class II(+/+) (MHC II(+/+))) that reach the lymph node surv...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Matthews, K, Qin, J, Yang, J, Hermans, I, Palmowski, M, Cerundolo, V, Ronchese, F
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2007