Fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): Application to 6-[18F]fluoro-l-DOPA
The Ag-mediated electrophilic [18F]fluorination of an arylboronic ester is reported. This new radiochemical transformation uses [ 18F]selectfluor bis(triflate) in acetone. The process gave 6-[ 18F]fluoro-l-DOPA with a RCY of 19 ± 12% and a specific activity of 2.6 ± 0.3 GBq μmol-1. © 2013 The Royal...
| Main Authors: | , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2013
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| _version_ | 1797101925864308736 |
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| author | Stenhagen, I Kirjavainen, A Forsback, S Jørgensen, C Robins, E Luthra, S Solin, O Gouverneur, V |
| author_facet | Stenhagen, I Kirjavainen, A Forsback, S Jørgensen, C Robins, E Luthra, S Solin, O Gouverneur, V |
| author_sort | Stenhagen, I |
| collection | OXFORD |
| description | The Ag-mediated electrophilic [18F]fluorination of an arylboronic ester is reported. This new radiochemical transformation uses [ 18F]selectfluor bis(triflate) in acetone. The process gave 6-[ 18F]fluoro-l-DOPA with a RCY of 19 ± 12% and a specific activity of 2.6 ± 0.3 GBq μmol-1. © 2013 The Royal Society of Chemistry. |
| first_indexed | 2024-03-07T05:58:47Z |
| format | Journal article |
| id | oxford-uuid:eb741aec-76bd-4eaf-b72d-1e4a0a35f949 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:58:47Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | oxford-uuid:eb741aec-76bd-4eaf-b72d-1e4a0a35f9492022-03-27T11:09:44ZFluorination of an arylboronic ester using [18F]selectfluor bis(triflate): Application to 6-[18F]fluoro-l-DOPAJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:eb741aec-76bd-4eaf-b72d-1e4a0a35f949EnglishSymplectic Elements at Oxford2013Stenhagen, IKirjavainen, AForsback, SJørgensen, CRobins, ELuthra, SSolin, OGouverneur, VThe Ag-mediated electrophilic [18F]fluorination of an arylboronic ester is reported. This new radiochemical transformation uses [ 18F]selectfluor bis(triflate) in acetone. The process gave 6-[ 18F]fluoro-l-DOPA with a RCY of 19 ± 12% and a specific activity of 2.6 ± 0.3 GBq μmol-1. © 2013 The Royal Society of Chemistry. |
| spellingShingle | Stenhagen, I Kirjavainen, A Forsback, S Jørgensen, C Robins, E Luthra, S Solin, O Gouverneur, V Fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): Application to 6-[18F]fluoro-l-DOPA |
| title | Fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): Application to 6-[18F]fluoro-l-DOPA |
| title_full | Fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): Application to 6-[18F]fluoro-l-DOPA |
| title_fullStr | Fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): Application to 6-[18F]fluoro-l-DOPA |
| title_full_unstemmed | Fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): Application to 6-[18F]fluoro-l-DOPA |
| title_short | Fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): Application to 6-[18F]fluoro-l-DOPA |
| title_sort | fluorination of an arylboronic ester using 18f selectfluor bis triflate application to 6 18f fluoro l dopa |
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