Interethnic studies of TNF polymorphisms confirm the likely presence of a second MHC susceptibility locus in ankylosing spondylitis.

Interethnic studies of TNF polymorphisms confirm the likely presence of a second MHC susceptibility locus in ankylosing spondylitis.

The objective of this study was to investigate TNF promoter region polymorphisms for association with susceptibility to ankylosing spondylitis (AS). The TNF -238 and -308 polymorphisms were genotyped in 306 English AS cases and 204 ethnically matched healthy B27-positive controls, and 96 southern Ge...

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Detalhes bibliográficos
Principais autores: Milicic, A, Lindheimer, F, Laval, S, Rudwaleit, M, Ackerman, H, Wordsworth, P, Hohler, T, Brown, M
Formato: Journal article
Idioma:English
Publicado em: 2000

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