Endocytosis of secretory granules in mouse pancreatic beta-cells evoked by transient elevation of cytosolic calcium.

Endocytosis of secretory granules in mouse pancreatic beta-cells evoked by transient elevation of cytosolic calcium.

1. To investigate the mechanisms regulating the reuptake of secretory granule membranes following regulated exocytosis, we have monitored changes in cell capacitance in single pancreatic beta-cells. 2. Membrane retrieval (endocytosis) occurred both in a continuous manner and in abrupt steps, corresp...

書目詳細資料
Main Authors:	Eliasson, L, Proks, P, Ammälä, C, Ashcroft, F, Bokvist, K, Renström, E, Rorsman, P, Smith, P
格式:	Journal article
語言:	English
出版:	1996

相似書籍

Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells.
由: Bokvist, K, et al.
出版: (1995)

RELATIONSHIP BETWEEN EXOCYTOSIS AND ENDOCYTOSIS IN PANCREATIC B-CELLS
由: Rorsman, P, et al.
出版: (1994)

CONTROL OF EXOCYTOSIS WITH B-CELL AT PROXIMAL AND DISTAL LEVELS OF THE SECRETORY CASCADE
由: Renstrom, E, et al.
出版: (1994)

CORRELATION OF INTERNAL CALCIUM TRANSIENTS, EXOCYTOSIS AND THE RELEASE OF GRANULE CONTENTS IN PANCREATIC BETA-CELLS
由: Smith, P, et al.
出版: (1994)

Rapid ATP-dependent priming of secretory granules precedes Ca(2+)-induced exocytosis in mouse pancreatic B-cells.
由: Eliasson, L, et al.
出版: (1997)

Stimulus-secretion coupling in pancreatic beta cells.
由: Ashcroft, F, et al.
出版: (1994)

TOLBUTAMIDE STIMULATES EXOCYTOSIS BY DIRECT INTERACTION WITH THE SECRETORY MACHINERY IN B-CELLS
由: Ammala, C, et al.
出版: (1993)

DIRECT EVIDENCE FOR THE EXISTENCE OF HOT-SPOTS OF SECRETION IN MOUSE PANCREATIC BETA-CELLS
由: Bokvist, K, et al.
出版: (1994)

Ca(2+)- and GTP-dependent exocytosis in mouse pancreatic beta-cells involves both common and distinct steps.
由: Proks, P, et al.
出版: (1996)

A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells.
由: Barg, S, et al.
出版: (2002)

CaM kinase II-dependent mobilization of secretory granules underlies acetylcholine-induced stimulation of exocytosis in mouse pancreatic B-cells.
由: Gromada, J, et al.
出版: (1999)

THE IMPORTANCE OF NA/CA-EXCHANGE IN RESTORING RESTING CYTOSOLIC CALCIUM LEVELS IN MOUSE BETA-CELLS
由: Bokvist, K, et al.
出版: (1995)

Exocytosis elicited by action potentials and voltage-clamp calcium currents in individual mouse pancreatic B-cells.
由: Ammälä, C, et al.
出版: (1993)

Inhibition of L-type calcium channels by internal GTP [gamma S] in mouse pancreatic beta cells.
由: Ammälä, C, et al.
出版: (1992)

Cooling inhibits exocytosis in single mouse pancreatic B-cells by suppression of granule mobilization.
由: Renström, E, et al.
出版: (1996)

LOCAL INTRACELLULAR CA2+-GRADIENTS ASSOCIATED WITH CA2+ ENTRY INTO AND SECRETION FROM MOUSE PANCREATIC BETA-CELLS
由: Bokvist, K, et al.
出版: (1993)

Calcium-independent potentiation of insulin release by cyclic AMP in single beta-cells.
由: Ammälä, C, et al.
出版: (1993)

Physical interaction between secretory granules and L-type calcium channels is required for fast exocytosis in B-cells
由: Renstrom, E, et al.
出版: (1998)

ATP-dependence of exocytosis in mouse pancreatic beta-cells
由: Eliasson, L, et al.
出版: (1997)

Effects of divalent cations on exocytosis and endocytosis from single mouse pancreatic beta-cells.
由: Proks, P, et al.
出版: (1995)

SULFONYLUREA AND EXOCYTOSIS IN MOUSE BETA-CELLS - A POSSIBLE INTERACTION WITH PROTEIN-KINASE-C
由: Ammala, C, et al.
出版: (1994)

Cytoplasmic calcium transients due to single action potentials and voltage-clamp depolarizations in mouse pancreatic B-cells.
由: Rorsman, P, et al.
出版: (1992)

Alpha 2-adrenoreceptor stimulation does not inhibit L-type calcium channels in mouse pancreatic beta-cells.
由: Bokvist, K, et al.
出版: (1991)

Insulin granule dynamics in pancreatic beta cells.
由: Rorsman, P, et al.
出版: (2003)

Diabetes - when insulin is trapped in the secretory granule?
由: Rorsman, P
出版: (2008)

Intracellular pH, cytosolic calcium concentration and electrical activity in RINm5F insulinoma cells.
由: Best, L, et al.
出版: (1994)

Separate processes mediate nucleotide-induced inhibition and stimulation of the ATP-regulated K(+)-channels in mouse pancreatic beta-cells.
由: Bokvist, K, et al.
出版: (1991)

Phosphatidylinositol 4-kinase serves as a metabolic sensor and regulates priming of secretory granules in pancreatic beta cells.
由: Olsen, H, et al.
出版: (2003)

Ion channels, electrical activity and insulin secretion.
由: Rorsman, P, et al.
出版: (1994)

Inhibition of ATP-regulated K(+)-channels by a photoactivatable ATP-analogue in mouse pancreatic beta-cells.
由: Ammälä, C, et al.
出版: (1991)

EXOCYTOSIS IN MOUSE PANCREATIC B-CELLS IS REGULATED BY THE BALANCE BETWEEN PHOSPHORYLATION AND DEPHOSPHORYLATION
由: Rorsman, P, et al.
出版: (1993)

Role for [Ca2+] microdomains in glucose-induced movement of GFP-tagged secretory granules.
由: Renstrom, E, et al.
出版: (1999)

Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.
由: Ammälä, C, et al.
出版: (1994)

A NOVEL LOW-CONDUCTANCE K+-CHANNEL PRODUCING MEMBRANE-POTENTIAL OSCILLATIONS IN MOUSE PANCREATIC BETA-CELLS
由: Bokvist, K, et al.
出版: (1992)

Demonstration of a novel apamin-insensitive calcium-activated K+ channel in mouse pancreatic B cells.
由: Ammälä, C, et al.
出版: (1993)

Glucagon-like peptide I increases cytoplasmic calcium in insulin-secreting beta TC3-cells by enhancement of intracellular calcium mobilization.
由: Gromada, J, et al.
出版: (1995)

Stimulation of the KATP channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic beta-cells.
由: Larsson, O, et al.
出版: (1993)

Cyclic AMP stimulates exocytosis in mouse B-cells by both PKA-dependent and PKA-independent mechanisms
由: Eliasson, L, et al.
出版: (1996)

Dynamics of the cationic, bioelectrical and secretory responses to formycin A in pancreatic islet cells.
由: Lebrun, P, et al.
出版: (1996)

Neurotransmitter-induced inhibition of exocytosis in insulin-secreting beta cells by activation of calcineurin.
由: Renström, E, et al.
出版: (1996)