Inhibitors of JmjC-containing histone demethylases

Histone demethylases (KDMs) catalyse the removal of N-methyl marks on histones and play important roles in epigenetic regulation. Abnormal histone methylation and dysregulation of KDMs have been linked to multiple diseases, and KDMs are emerging as promising therapeutic targets. This chapter provide...

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Bibliographic Details
Main Authors: Wright, M, Kawamura, A, Brennan, PE
Other Authors: Mai, A
Format: Book section
Language:English
Published: Springer 2020