Questioning the methodologic superiority of 'placebo' over 'active' controlled trials.

A resilient issue in research ethics is whether and when a placebo-controlled trial (PCT) is justified if it deprives research subjects of a recognized treatment. The clinicians' moral duty to provide the best available care seems to require the use of 'active' controlled trials (ACTs...

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Autor principal: Howick, J
Format: Journal article
Idioma:English
Publicat: 2009