Genomic patterns of progression in smoldering multiple myeloma

We analyzed whole genomes of unique paired samples from smoldering multiple myeloma (SMM) patients progressing to multiple myeloma (MM). We report that the genomic landscape, including mutational profile and structural rearrangements at the smoldering stage is very similar to MM. Paired sample analy...

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Bibliografische gegevens
Hoofdauteurs: Bolli, N, Maura, F, Minvielle, S, Gloznik, D, Szalat, R, Fullam, A, Martincorena, I, Dawson, K, Samur, M, Zamora, J, Tarpey, P, Davies, H, Fulciniti, M, Shammas, M, Tai, Y, Magrangeas, F, Moreau, P, Corradini, P, Anderson, K, Alexandrov, L, Wedge, D, Avet-Loiseau, H, Campbell, P, Munshi, N
Formaat: Journal article
Gepubliceerd in: Nature Publishing Group 2018