Semi-supervised coronary vessels segmentation from invasive coronary angiography with connectivity-preserving loss function

The segmentation of arteries in invasive coronary angiography is necessary to build quantitative models and eventually improve the diagnosis of cardiovascular diseases. Standard segmentation algorithms suffer due to the lack of fully annotated datasets and tend to return disconnected vessels. Thus,...

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Main Authors: He, H, Banerjee, A, Beetz, M, Choudhury, RP, Grau, V, Ieee
Format: Conference item
Language:English
Published: IEEE 2022
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author He, H
Banerjee, A
Beetz, M
Choudhury, RP
Grau, V
Ieee
author_facet He, H
Banerjee, A
Beetz, M
Choudhury, RP
Grau, V
Ieee
author_sort He, H
collection OXFORD
description The segmentation of arteries in invasive coronary angiography is necessary to build quantitative models and eventually improve the diagnosis of cardiovascular diseases. Standard segmentation algorithms suffer due to the lack of fully annotated datasets and tend to return disconnected vessels. Thus, we explore a semi-supervised segmentation framework to address these issues. Specifically, we use a student model and a teacher model as the main framework with Nested U-Nets (UNet++) as their backbones. The student model learns by minimizing a segmentation loss between the output and the ground truth, and a consistency loss guided by the uncertainty information. Additionally, a special loss function based on elastic interaction is used to improve the connectivity of arterial branches. We demonstrate the effectiveness of our proposed techniques over 42 labeled and 60 unlabeled samples and find relative improvement of 5.59% for Dice score and 69.99% for Betti number compared to a U-Net.
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spelling oxford-uuid:ebb4ba88-a555-4738-9409-3022ff86fa2e2022-11-09T12:28:07ZSemi-supervised coronary vessels segmentation from invasive coronary angiography with connectivity-preserving loss functionConference itemhttp://purl.org/coar/resource_type/c_5794uuid:ebb4ba88-a555-4738-9409-3022ff86fa2eEnglishSymplectic ElementsIEEE2022He, HBanerjee, ABeetz, MChoudhury, RPGrau, VIeeeThe segmentation of arteries in invasive coronary angiography is necessary to build quantitative models and eventually improve the diagnosis of cardiovascular diseases. Standard segmentation algorithms suffer due to the lack of fully annotated datasets and tend to return disconnected vessels. Thus, we explore a semi-supervised segmentation framework to address these issues. Specifically, we use a student model and a teacher model as the main framework with Nested U-Nets (UNet++) as their backbones. The student model learns by minimizing a segmentation loss between the output and the ground truth, and a consistency loss guided by the uncertainty information. Additionally, a special loss function based on elastic interaction is used to improve the connectivity of arterial branches. We demonstrate the effectiveness of our proposed techniques over 42 labeled and 60 unlabeled samples and find relative improvement of 5.59% for Dice score and 69.99% for Betti number compared to a U-Net.
spellingShingle He, H
Banerjee, A
Beetz, M
Choudhury, RP
Grau, V
Ieee
Semi-supervised coronary vessels segmentation from invasive coronary angiography with connectivity-preserving loss function
title Semi-supervised coronary vessels segmentation from invasive coronary angiography with connectivity-preserving loss function
title_full Semi-supervised coronary vessels segmentation from invasive coronary angiography with connectivity-preserving loss function
title_fullStr Semi-supervised coronary vessels segmentation from invasive coronary angiography with connectivity-preserving loss function
title_full_unstemmed Semi-supervised coronary vessels segmentation from invasive coronary angiography with connectivity-preserving loss function
title_short Semi-supervised coronary vessels segmentation from invasive coronary angiography with connectivity-preserving loss function
title_sort semi supervised coronary vessels segmentation from invasive coronary angiography with connectivity preserving loss function
work_keys_str_mv AT heh semisupervisedcoronaryvesselssegmentationfrominvasivecoronaryangiographywithconnectivitypreservinglossfunction
AT banerjeea semisupervisedcoronaryvesselssegmentationfrominvasivecoronaryangiographywithconnectivitypreservinglossfunction
AT beetzm semisupervisedcoronaryvesselssegmentationfrominvasivecoronaryangiographywithconnectivitypreservinglossfunction
AT choudhuryrp semisupervisedcoronaryvesselssegmentationfrominvasivecoronaryangiographywithconnectivitypreservinglossfunction
AT grauv semisupervisedcoronaryvesselssegmentationfrominvasivecoronaryangiographywithconnectivitypreservinglossfunction
AT ieee semisupervisedcoronaryvesselssegmentationfrominvasivecoronaryangiographywithconnectivitypreservinglossfunction