Rapid eye movement sleep behavior disorder and potassium channel antibody-associated limbic encephalitis.
Of six patients registered in our center with nonparaneoplastic limbic encephalitis associated with antibodies to voltage-gated potassium channels, the five men had rapid eye movement sleep behavior disorder (RBD) coincident with voltage-gated potassium channel antibody-associated limbic encephaliti...
| Huvudupphovsmän: | , , , , , , , , |
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| Materialtyp: | Journal article |
| Språk: | English |
| Publicerad: |
2006
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| _version_ | 1826303243517427712 |
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| author | Iranzo, A Graus, F Clover, L Morera, J Bruna, J Vilar, C Martínez-Rodriguez, J Vincent, A Santamaría, J |
| author_facet | Iranzo, A Graus, F Clover, L Morera, J Bruna, J Vilar, C Martínez-Rodriguez, J Vincent, A Santamaría, J |
| author_sort | Iranzo, A |
| collection | OXFORD |
| description | Of six patients registered in our center with nonparaneoplastic limbic encephalitis associated with antibodies to voltage-gated potassium channels, the five men had rapid eye movement sleep behavior disorder (RBD) coincident with voltage-gated potassium channel antibody-associated limbic encephalitis onset. In three patients, immunosuppression resulted in resolution of RBD in parallel with remission of the limbic syndrome. RBD persisted in two patients with partial resolution of the limbic syndrome. Our findings suggest that RBD is frequent in the setting of voltage-gated potassium channel antibody-associated limbic encephalitis and can be related to autoimmune-mediated mechanisms. In addition, these observations suggest that impairment of the limbic system may play a role in the pathogenesis of RBD. |
| first_indexed | 2024-03-07T05:59:42Z |
| format | Journal article |
| id | oxford-uuid:ebbe43be-d1db-4e7c-a7e2-759f8ff2c3d9 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T05:59:42Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | oxford-uuid:ebbe43be-d1db-4e7c-a7e2-759f8ff2c3d92022-03-27T11:12:07ZRapid eye movement sleep behavior disorder and potassium channel antibody-associated limbic encephalitis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ebbe43be-d1db-4e7c-a7e2-759f8ff2c3d9EnglishSymplectic Elements at Oxford2006Iranzo, AGraus, FClover, LMorera, JBruna, JVilar, CMartínez-Rodriguez, JVincent, ASantamaría, JOf six patients registered in our center with nonparaneoplastic limbic encephalitis associated with antibodies to voltage-gated potassium channels, the five men had rapid eye movement sleep behavior disorder (RBD) coincident with voltage-gated potassium channel antibody-associated limbic encephalitis onset. In three patients, immunosuppression resulted in resolution of RBD in parallel with remission of the limbic syndrome. RBD persisted in two patients with partial resolution of the limbic syndrome. Our findings suggest that RBD is frequent in the setting of voltage-gated potassium channel antibody-associated limbic encephalitis and can be related to autoimmune-mediated mechanisms. In addition, these observations suggest that impairment of the limbic system may play a role in the pathogenesis of RBD. |
| spellingShingle | Iranzo, A Graus, F Clover, L Morera, J Bruna, J Vilar, C Martínez-Rodriguez, J Vincent, A Santamaría, J Rapid eye movement sleep behavior disorder and potassium channel antibody-associated limbic encephalitis. |
| title | Rapid eye movement sleep behavior disorder and potassium channel antibody-associated limbic encephalitis. |
| title_full | Rapid eye movement sleep behavior disorder and potassium channel antibody-associated limbic encephalitis. |
| title_fullStr | Rapid eye movement sleep behavior disorder and potassium channel antibody-associated limbic encephalitis. |
| title_full_unstemmed | Rapid eye movement sleep behavior disorder and potassium channel antibody-associated limbic encephalitis. |
| title_short | Rapid eye movement sleep behavior disorder and potassium channel antibody-associated limbic encephalitis. |
| title_sort | rapid eye movement sleep behavior disorder and potassium channel antibody associated limbic encephalitis |
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