Functional impact of genetic polymorphisms in NAD(P)H oxidase p22phox subunit on vascular superoxide production in atherosclerosis

Background: Increased superoxide (SO) production is an important aspect of vascular disease states. The principal source of vascular SO is NAD(P)H oxidase. Some case control studies suggest an association between coronary artery disease and polymorphisms in the p22phox gene encoding the p22 subunit...

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Main Authors: Guzik, T, West, N, Black, E, McDonald, D, Ratnatunga, C, Pillai, R, Channon, K
格式: Journal article
语言:English
出版: 2000