Prospective technical validation and assessment of intra-tumour heterogeneity of a low density array hypoxia gene profile in head and neck squamous cell carcinoma.

BACKGROUND AND PURPOSE: Tumour hypoxia is associated with a poor prognosis in head and neck squamous cell carcinoma (HNSCC), however there is no accepted method for assessing hypoxia clinically. We aimed to conduct a technical validation of a hypoxia gene expression signature using the TaqMan Low De...

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Hlavní autoři: Betts, G, Eustace, A, Patiar, S, Valentine, H, Irlam, J, Ramachandran, A, Merve, A, Homer, J, Möller-Levet, C, Buffa, F, Hall, G, Miller, C, Harris, A, West, C
Médium: Journal article
Jazyk:English
Vydáno: 2013