CaM kinase II-dependent mobilization of secretory granules underlies acetylcholine-induced stimulation of exocytosis in mouse pancreatic B-cells.
1. Measurements of cell capacitance were used to investigate the mechanisms by which acetylcholine (ACh) stimulates Ca2+-induced exocytosis in single insulin-secreting mouse pancreatic B-cells. 2. ACh (250 microM) increased exocytotic responses elicited by voltage-clamp depolarizations 2.3-fold. Thi...
المؤلفون الرئيسيون: | Gromada, J, Høy, M, Renström, E, Bokvist, K, Eliasson, L, Göpel, S, Rorsman, P |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
1999
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مواد مشابهة
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Acetylcholine stimulates exocytosis by acceleration of granula mobilisation in mouse pancreatic B-cells
حسب: Gromada, J, وآخرون
منشور في: (1998) -
Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells.
حسب: Bokvist, K, وآخرون
منشور في: (1995) -
Rapid ATP-dependent priming of secretory granules precedes Ca(2+)-induced exocytosis in mouse pancreatic B-cells.
حسب: Eliasson, L, وآخرون
منشور في: (1997) -
Cooling inhibits exocytosis in single mouse pancreatic B-cells by suppression of granule mobilization.
حسب: Renström, E, وآخرون
منشور في: (1996) -
Somatostatin inhibits exocytosis in rat pancreatic alpha-cells by G(i2)-dependent activation of calcineurin and depriming of secretory granules.
حسب: Gromada, J, وآخرون
منشور في: (2001)