Distinctive properties of the hyaluronan-binding domain in the lymphatic endothelial receptor Lyve-1 and their implications for receptor function.

The lymphatic endothelial hyaluronan (HA) receptor Lyve-1 is a member of the Link protein superfamily most similar to the leukocyte HA receptor CD44. However, the structure of Lyve-1 and the nature of its interaction with ligand are obscure. Here we present new evidence that Lyve-1 is functionally d...

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Detalles Bibliográficos
Autores principales: Banerji, S, Hide, B, James, JR, Noble, M, Jackson, D
Formato: Journal article
Lenguaje:English
Publicado: 2010