Mutagenesis of conserved tryptophan residues within the receptor-binding domain of intimin: influence on binding activity and virulence.

Mutagenesis of conserved tryptophan residues within the receptor-binding domain of intimin: influence on binding activity and virulence.

Toon andere (1) versies

Intimate bacterial adhesion to intestinal epithelium is a pathogenic mechanism shared by several human and animal enteric pathogens, including enteropathogenic and enterohaemorrhagic Escherichia coli and Citrobacter rodentium. The proteins directly involved in this process are the outer-membrane adh...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs:	Reece, S, Simmons, C, Fitzhenry, R, Batchelor, M, Hale, C, Matthews, S, Phillips, A, Dougan, G, Frankel, G
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	2002

Gelijkaardige items

Mutagenesis of conserved tryptophan residues within the receptor-binding domain of intimin: influence on binding activity and virulence
door: Reece, S, et al.
Gepubliceerd in: (2002)

Site-directed mutagenesis of intimin alpha modulates intimin-mediated tissue tropism and host specificity.
door: Reece, S, et al.
Gepubliceerd in: (2001)

Tyrosine residues at the immunoglobulin-C-type lectin inter-domain boundary of intimin are not involved in Tir-binding but implicated in colonisation of the host
door: Reece, S, et al.
Gepubliceerd in: (2002)

Tyrosine residues at the immunoglobulin-C-type lectin inter-domain boundary of intimin are not involved in Tir-binding but implicated in colonisation of the host.
door: Reece, S, et al.
Gepubliceerd in: (2002)

Intimin-specific immune responses prevent bacterial colonization by the attaching-effacing pathogen Citrobacter rodentium
door: Ghaem-Maghami, M, et al.
Gepubliceerd in: (2001)

Intimin-specific immune responses prevent bacterial colonization by the attaching-effacing pathogen Citrobacter rodentium.
door: Ghaem-Maghami, M, et al.
Gepubliceerd in: (2001)

ANALYSIS OF THE HIV ENVELOPE BINDING DOMAIN ON CD4 THROUGH SITE-DIRECTED MUTAGENESIS
door: Arthos, J, et al.
Gepubliceerd in: (1990)

Mutagenesis studies on the iron binding ligands of clavaminic acid synthase.
door: Doan, L, et al.
Gepubliceerd in: (2000)

Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms.
door: Elkins, J, et al.
Gepubliceerd in: (2010)

Characterization of the sialic acid-binding site in sialoadhesin by site-directed mutagenesis.
door: Vinson, M, et al.
Gepubliceerd in: (1996)

Mutagenesis of the Peptide Inhibitor of ASIC3 Channel Introduces Binding to Thumb Domain of ASIC1a but Reduces Analgesic Activity
door: Timur A. Khasanov, et al.
Gepubliceerd in: (2024-08-01)

Molecular contacts in the transmembrane c-subunit oligomer of F-ATPases identified by tryptophan substitution mutagenesis.
door: Schnick, C, et al.
Gepubliceerd in: (2000)

Unbiased mutagenesis of MHV68 LANA reveals a DNA-binding domain required for LANA function in vitro and in vivo.
door: Clinton R Paden, et al.
Gepubliceerd in: (2012-09-01)

1H-NMR characterization of L-tryptophan binding to TRAP, the trp RNA-binding attenuation protein of Bacillus subtilis.
door: Ramesh, V, et al.
Gepubliceerd in: (1996)

The SH3-binding domain of chorismate mutase protein of Mycobacterium tuberculosis contributes to mycobacterial virulence
door: Ravi Pal, et al.
Gepubliceerd in: (2024-11-01)

RNA aptamers binding the double-stranded RNA-binding domain.
door: Hallegger, M, et al.
Gepubliceerd in: (2006)

Novel sterol binding domains in bacteria
door: Liting Zhai, et al.
Gepubliceerd in: (2024-02-01)

Rational Design of New Binding Specificity by Simultaneous Mutagenesis of Calmodulin and a Target Peptide
door: Green, David F., et al.
Gepubliceerd in: (2012)

Site-directed mutagenesis of the CC chemokine binding protein 35K-Fc reveals residues essential for activity and mutations that increase the potency of CC chemokine blockade.
door: White, G, et al.
Gepubliceerd in: (2011)

Structure and association of ATP-binding cassette transporter nucleotide-binding domains
door: Kerr, I
Gepubliceerd in: (2002)

Key residues for membrane binding, oligomerization, and pore forming activity of staphylococcal alpha-hemolysin identified by cysteine scanning mutagenesis and targeted chemical modification.
door: Walker, B, et al.
Gepubliceerd in: (1995)

Identifying small molecule binding sites for epigenetic proteins at domain-domain interfaces
door: Brennan, P, et al.
Gepubliceerd in: (2018)

Site-directed mutagenesis of p97/VCP to gain insight on the role of ATP binding to D1 domain affecting adaptor protein selectivity.
door: Rizal Ismail.
Gepubliceerd in: (2013)

The streptococcal binding site in the gelatin-binding domain of fibronectin is consistent with a non-linear arrangement of modules.
door: Atkin, K, et al.
Gepubliceerd in: (2010)

Mutagenesis and characterization studies of E. Coli DNA-binding protein from starved cells (DPS)
door: Ang, Emmiline Xiao Wei
Gepubliceerd in: (2010)

Construction of an infectious clone for enterovirus A89 and mutagenesis analysis of viral infection and cell binding
door: Jingjing Yan, et al.
Gepubliceerd in: (2024-04-01)

Metal-catalyzed oxidation and mutagenesis studies on the iron(II) binding site of 1-aminocyclopropane-1-carboxylate oxidase.
door: Zhang, Z, et al.
Gepubliceerd in: (1997)

Modulation of the ligand binding properties of the transcription repressor NmrA by GATA-containing DNA and site-directed mutagenesis.
door: Lamb, H, et al.
Gepubliceerd in: (2004)

In silico mutation of cysteine residues in the ligand-binding domain of an N-methyl-D-aspartate receptor.
door: Kaye, S, et al.
Gepubliceerd in: (2007)

Localization of the binding site of the C-terminal domain of cardiac myosin-binding protein-C on the myosin rod.
door: Flashman, E, et al.
Gepubliceerd in: (2007)

TSG-6 binds via its CUB_C domain to the cell-binding domain of fibronectin and increases fibronectin matrix assembly.
door: Kuznetsova, SA, et al.
Gepubliceerd in: (2008)

ATP/ADP binding to a novel nucleotide binding domain of the reticulocyte-binding protein Py235 of Plasmodium yoelii
door: Ramalingam, Jeya Kumar, et al.
Gepubliceerd in: (2011)

Identification of the residues in human CD4 critical for the binding of HIV.
door: Arthos, J, et al.
Gepubliceerd in: (1989)

A Ubiquitin-binding domain that binds a structural fold distinct from that of Ubiquitin
door: Lim, M, et al.
Gepubliceerd in: (2019)

Binding behavior of receptor binding domain of the SARS-CoV-2 virus and ivermectin
door: Kasidy R. Gossen, et al.
Gepubliceerd in: (2024-02-01)

Residues on both faces of the first immunoglobulin fold contribute to homophilic binding sites of PECAM-1/CD31.
door: Newton, J, et al.
Gepubliceerd in: (1997)

Role of N1-Domain, Linker, N2-Domain, and Latch in the Binding Activity and Stability of the Collagen-Binding Domain for the Collagen-Binding Protein Cbm from <i>Streptococcus mutans</i>
door: Akari Nishi, et al.
Gepubliceerd in: (2024-04-01)

Site directed mutagenesis of miRNA binding site on the 3′-UTR of choline kinase alpha gene
door: Bnisallama, Faisal Fayez Saffah
Gepubliceerd in: (2022)

Determination of the Cannabinoid CB1 Receptor’s Positive Allosteric Modulator Binding Site through Mutagenesis Studies
door: Hayley M. Green, et al.
Gepubliceerd in: (2024-01-01)

Urea Denaturation, Zinc Binding, and DNA Binding Assays of Mutant p53 DNA-binding Domains and Full-length Proteins
door: Jeung- Ha, et al.
Gepubliceerd in: (2021-10-01)