Interaction of HLA-B27 homodimers with KIR3DL1 and KIR3DL2, unlike HLA-B27 heterotrimers, is independent of the sequence of bound peptide.

Interaction of HLA-B27 homodimers with KIR3DL1 and KIR3DL2, unlike HLA-B27 heterotrimers, is independent of the sequence of bound peptide.

HLA-B27 can form beta-2 microglobulin (beta2m)-associated heterotrimers (HLA-B27) and beta2m-free homodimers (B27(2)). Here, we study the role of complexed peptide in the interaction of these forms of B27 with the killer cell immunoglobulin (Ig)-like receptors KIR3DL1 and KIR3DL2 and with Ig-like tr...

Full description

Bibliographic Details
Main Authors:	Kollnberger, S, Chan, A, Sun, M, Chen, L, Wright, C, di Gleria, K, McMichael, A, Bowness, P
Format:	Journal article
Language:	English
Published:	2007

Similar Items

HLA-B27 homodimers differ in their interactions with LILRB1, LILRB2, KIR3DL1 and KIR3DL2 compared to HLA-B27 heterotrimers
by: Giles, J, et al.
Published: (2010)

Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in ankylosing spondylitis.
by: Bowness, P, et al.
Published: (2011)

THE ROLE OF HLA-B27 KIR3DL2 INTERACTIONS IN THE PATHOGENESIS OF SPONDYLOARTHRITIS
by: Kollnberger, S, et al.
Published: (2012)

The KIRs of HLA-B27: the role of HLA-B27 KIR interactions in infection and spondyloarthritis
by: Wong-Baeza, I, et al.
Published: (2011)

Molecular determinants for KIR3DL2 binding to HLA-B27 and other HLA-class I ligands
by: Hatano, H, et al.
Published: (2013)

HLA-B27 and KIR3DL2 Interactions Promote The Differentiation and Survival Of Proinflammatory T Cells In Spondyloarthritis
by: Ridley, A, et al.
Published: (2013)

KIR3DL2 INTERACTION WITH HLA-B27 PROMOTES THE SURVIVAL OF TH17 CELLS IN ANKYLOSING SPONDYLITIS
by: Kollnberger, S, et al.
Published: (2010)

Crystal structures and KIR3DL1 recognition of three immunodominant viral peptides complexed to HLA-B*2705.
by: Stewart-Jones, G, et al.
Published: (2005)

KIR3DL2 INTERACTION WITH HLA-B27 PROMOTES THE SURVIVAL OF TH17 CELLS IN ANKYLOSING SPONDYLITIS
by: Kollnberger, S, et al.
Published: (2010)

THE ARTHRITIS-ASSOCIATED HLA-B(star)27:05 FORMS MORE CELL SURFACE B27 DIMER AND FREE HEAVY CHAIN LIGANDS FOR KIR3DL2 AND LILRB2 IMMUNORECEPTORS THAN HLA(star)B27:09
by: Shaw, J, et al.
Published: (2013)

The arthritis-associated HLA-B*27:05 allele forms more cell surface B27 dimer and free heavy chain ligands for KIR3DL2 than HLA-B*27:09.
by: Cauli, A, et al.
Published: (2013)

Identification and characterisation of cell surface HLA-B27 homodimers
by: Bird, L, et al.
Published: (2002)

HLA-B27 transgenic rodents express cell surface HLA-B27 heavy chain homodimers and multimers.
by: Bowness, P, et al.
Published: (2003)

HLA-B27 FORMS HEAVY CHAIN HOMODIMERS IN VITRO AND IN VIVO THAT BIND TO CELLULAR RECEPTORS INCLUDING LILR AND KIR FAMILY MEMBERS
by: McHugh, K, et al.
Published: (2010)

Conjunctival scarring in trachoma is associated with the HLA-C ligand of KIR and is exacerbated by heterozygosity at KIR2DL2/KIR2DL3.
by: Chrissy H Roberts, et al.
Published: (2014-03-01)

KIR3DL2 Binds to HLA-B27 Dimers and Free H Chains More Strongly than Other HLA Class I and Promotes the Expansion of T Cells in Ankylosing Spondylitis.
by: Wong-Baeza, I, et al.
Published: (2013)

KIR3DL2 binds to HLA-B27 dimers and free H chains more strongly than other HLA class I and promotes the expansion of T cells in ankylosing spondylitis.
by: Wong-Baeza, I, et al.
Published: (2013)

Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C
by: Shoeib Moradi, et al.
Published: (2021-04-01)

Cell-surface expression and immune receptor recognition of HLA-B27 homodimers.
by: Kollnberger, S, et al.
Published: (2002)

Influence of Glycosylation Inhibition on the Binding of KIR3DL1 to HLA-B*57:01.
by: Wilhelm Salzberger, et al.
Published: (2015-01-01)

Recognition of HLA-A3 and HLA-A11 by KIR3DL2 is peptide-specific.
by: Hansasuta, P, et al.
Published: (2004)

KIR2DL2, KIR2DL5A and KIR2DL5B genes induce susceptibility to dengue virus infection while KIR3DL3 and KIR2DS5 confers protection
by: Aziz Sidi Aristide TAPSOBA, et al.
Published: (2022-10-01)

Significant association of KIR2DL3-HLA-C1 combination with cerebral malaria and implications for co-evolution of KIR and HLA.
by: Kouyuki Hirayasu, et al.
Published: (2012-01-01)

HLA-B*2709 FORMS LESS CELL SURFACE B27 DIMER AND FREE HEAVY CHAIN LIGANDS FOR KIR3DL2 AND LILRB2 IMMUNORECEPTORS THAN ARTHRITIS-ASSOCIATED HLA-B*2705
by: Shaw, J, et al.
Published: (2012)

Functional characterisation of HLA-B27 in autoimmunity
by: Kollnberger, S, et al.
Published: (2001)

HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors.
by: Kollnberger, S, et al.
Published: (2004)

Diverse functionality among NK cell receptors for the C1 epitope of HLA-C: KIR2DS2, KIR2DL2, and KIR2DL3
by: Achim K. Moesta, et al.
Published: (2012-11-01)

Cutting Edge: Allele-specific and peptide-dependent interactions between KIR3DL1 and HLA-A and HLA-B.
by: Thananchai, H, et al.
Published: (2007)

Cutting edge: Allele-specific and peptide-dependent interactions between KIR3DL1 and HLA-A and HLA-B
by: Thananchai, H, et al.
Published: (2007)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
by: Bowness, P, et al.
Published: (2010)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
by: Bowness, P, et al.
Published: (2010)

Follicular lymphoma patients with KIR2DL2 and KIR3DL1 and their ligands (HLA-C1 and HLA-Bw4) show improved outcome when receiving rituximab
by: Amy K. Erbe, et al.
Published: (2019-03-01)

HLA-B-27 heavy chain homodimer formation and natural killer cell family interaction - comparison of two HLA-B-27 subtypes in vitro
by: Giles, J, et al.
Published: (2008)

Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling.
by: Bird, L, et al.
Published: (2003)

HLA-B27-Homodimer-Specific Antibody Modulates the Expansion of Pro-Inflammatory T-Cells in HLA-B27 Transgenic Rats.
by: Osiris Marroquin Belaunzaran, et al.
Published: (2015-01-01)

The pathogenesis of spondyloarthritides - HLA-B-27 homodimer expression on human monocyte/macrophage cell lines
by: McHugh, K, et al.
Published: (2008)

The role of KIR2DL3/HLA-C*0802 in Brazilian patients with rheumatoid vasculitis
by: Wester Eidi Nishimura, et al.
Published: (2015-06-01)

Molecular Characterisation Of The Killer Cell Immunoglobulin-Like Receptor 3DL2 Binding To Aberrant HLA-B27 Heavy Chains In Spondyloarthritis
by: Hatano, H, et al.
Published: (2013)

KIR And HLA Haplotype Analysis in a Family Lacking The KIR 2DL1-2DP1 Genes
by: Vojvodić Svetlana, et al.
Published: (2015-06-01)

NK Cells Expressing the Inhibitory Killer Immunoglobulin-Like Receptors (iKIR) KIR2DL1, KIR2DL3 and KIR3DL1 Are Less Likely to Be CD16+ than Their iKIR Negative Counterparts.
by: Gamze Isitman, et al.
Published: (2016-01-01)