Virtual reality in the treatment of persecutory delusions: Randomised controlled experimental study testing how to reduce delusional conviction

Background Persecutory delusions may be unfounded threat beliefs maintained by safety-seeking behaviours that prevent disconfirmatory evidence being successfully processed. Use of virtual reality could facilitate new learning. Aims To test the hypothesis that enabling patients to test the threat pre...

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Main Authors: Freeman, D, Bradley, J, Antley, A, Bourke, E, Deweever, N, Evans, N, Černis, E, Sheaves, B, Waite, F, Dunn, G, Slater, M, Clark, D
Format: Journal article
Language:English
Published: Cambridge University Press 2016
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author Freeman, D
Bradley, J
Antley, A
Bourke, E
Deweever, N
Evans, N
Černis, E
Sheaves, B
Waite, F
Dunn, G
Slater, M
Clark, D
author_facet Freeman, D
Bradley, J
Antley, A
Bourke, E
Deweever, N
Evans, N
Černis, E
Sheaves, B
Waite, F
Dunn, G
Slater, M
Clark, D
author_sort Freeman, D
collection OXFORD
description Background Persecutory delusions may be unfounded threat beliefs maintained by safety-seeking behaviours that prevent disconfirmatory evidence being successfully processed. Use of virtual reality could facilitate new learning. Aims To test the hypothesis that enabling patients to test the threat predictions of persecutory delusions in virtual reality social environments with the dropping of safety-seeking behaviours (virtual reality cognitive therapy) would lead to greater delusion reduction than exposure alone (virtual reality exposure). Method Conviction in delusions and distress in a real-world situation were assessed in 30 patients with persecutory delusions. Patients were then randomised to virtual reality cognitive therapy or virtual reality exposure, both with 30 min in graded virtual reality social environments. Delusion conviction and real-world distress were then reassessed. Results In comparison with exposure, virtual reality cognitive therapy led to large reductions in delusional conviction (reduction 22.0%, P = 0.024, Cohen's d = 1.3) and real-world distress (reduction 19.6%, P = 0.020, Cohen's d = 0.8). Conclusion Cognitive therapy using virtual reality could prove highly effective in treating delusions.
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spelling oxford-uuid:ec2dea49-280d-4667-9767-b9ad0c0466292022-03-27T11:15:33ZVirtual reality in the treatment of persecutory delusions: Randomised controlled experimental study testing how to reduce delusional convictionJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:ec2dea49-280d-4667-9767-b9ad0c046629EnglishSymplectic Elements at OxfordCambridge University Press2016Freeman, DBradley, JAntley, ABourke, EDeweever, NEvans, NČernis, ESheaves, BWaite, FDunn, GSlater, MClark, DBackground Persecutory delusions may be unfounded threat beliefs maintained by safety-seeking behaviours that prevent disconfirmatory evidence being successfully processed. Use of virtual reality could facilitate new learning. Aims To test the hypothesis that enabling patients to test the threat predictions of persecutory delusions in virtual reality social environments with the dropping of safety-seeking behaviours (virtual reality cognitive therapy) would lead to greater delusion reduction than exposure alone (virtual reality exposure). Method Conviction in delusions and distress in a real-world situation were assessed in 30 patients with persecutory delusions. Patients were then randomised to virtual reality cognitive therapy or virtual reality exposure, both with 30 min in graded virtual reality social environments. Delusion conviction and real-world distress were then reassessed. Results In comparison with exposure, virtual reality cognitive therapy led to large reductions in delusional conviction (reduction 22.0%, P = 0.024, Cohen's d = 1.3) and real-world distress (reduction 19.6%, P = 0.020, Cohen's d = 0.8). Conclusion Cognitive therapy using virtual reality could prove highly effective in treating delusions.
spellingShingle Freeman, D
Bradley, J
Antley, A
Bourke, E
Deweever, N
Evans, N
Černis, E
Sheaves, B
Waite, F
Dunn, G
Slater, M
Clark, D
Virtual reality in the treatment of persecutory delusions: Randomised controlled experimental study testing how to reduce delusional conviction
title Virtual reality in the treatment of persecutory delusions: Randomised controlled experimental study testing how to reduce delusional conviction
title_full Virtual reality in the treatment of persecutory delusions: Randomised controlled experimental study testing how to reduce delusional conviction
title_fullStr Virtual reality in the treatment of persecutory delusions: Randomised controlled experimental study testing how to reduce delusional conviction
title_full_unstemmed Virtual reality in the treatment of persecutory delusions: Randomised controlled experimental study testing how to reduce delusional conviction
title_short Virtual reality in the treatment of persecutory delusions: Randomised controlled experimental study testing how to reduce delusional conviction
title_sort virtual reality in the treatment of persecutory delusions randomised controlled experimental study testing how to reduce delusional conviction
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