Multi-population classical HLA type imputation

Statistical imputation of classical HLA alleles in case-control studies has become established as a valuable tool for identifying and fine-mapping signals of disease association in the MHC. Imputation into diverse populations has, however, remained challenging, mainly because of the additional haplo...

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Detalles Bibliográficos
Autores principales: Dilthey, A, Leslie, S, Moutsianas, L, Shen, J, Cox, C, Nelson, MR, McVean, G
Formato: Journal article
Lenguaje:English
Publicado: Public Library of Science 2013