Strong TCR conservation and altered T cell cross-reactivity characterize a B*57-restricted immune response in HIV-1 infection.

Strong TCR conservation and altered T cell cross-reactivity characterize a B*57-restricted immune response in HIV-1 infection.

HLA-B*57 is associated with slower disease progression to AIDS, and CD8+ T cell responses to B*57-restricted epitopes are thought to contribute to this protective effect. In this study, we evaluate the B*57-restricted p24 KAFSPEVIPMF (KF11) immune response which is immunodominant during chronic infe...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Gillespie, G, Stewart-Jones, G, Rengasamy, J, Beattie, T, Bwayo, J, Plummer, F, Kaul, R, Mcmichael, A, Easterbrook, P, Dong, T, Jones, E, Rowland-Jones, S
التنسيق:	Journal article
اللغة:	English
منشور في:	2006

مواد مشابهة

Cross-reactive cytotoxic T lymphocytes against a HIV-1 p24 epitope in slow progressors with B*57.
حسب: Gillespie, G, وآخرون
منشور في: (2002)

Identification of a novel HLA B*57 restricted cytotoxic T-lymphocyte epitope within HIV-1 rev.
حسب: Makadzange, A, وآخرون
منشور في: (2006)

Characterization of an HLA-C-restricted CTL response in chronic HIV infection.
حسب: Makadzange, A, وآخرون
منشور في: (2010)

T cell cross-reactivity and conformational changes during TCR engagement.
حسب: Lee, J, وآخرون
منشور في: (2004)

Gonococcal cervicitis is associated with reduced systemic CD8+ T cell responses in human immunodeficiency virus type 1-infected and exposed, uninfected sex workers.
حسب: Kaul, R, وآخرون
منشور في: (2002)

HLA typing in a Kenyan cohort identifies novel class I alleles that restrict cytotoxic T-cell responses to local HIV-1 clades.
حسب: Bird, T, وآخرون
منشور في: (2002)

Screening for HIV-specific T-cell responses using overlapping 15-mer peptide pools or optimized epitopes.
حسب: Beattie, T, وآخرون
منشور في: (2004)

How important is the 'quality' of the cytotoxic T lymphocyte (CTL) response in protection against HIV infection?
حسب: Rowland-Jones, S, وآخرون
منشور في: (2001)

Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms.
حسب: Stewart-Jones, G, وآخرون
منشور في: (2012)

Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms.
حسب: Stewart-Jones, G, وآخرون
منشور في: (2012)

Structures of three HIV-1 HLA-B*5703-peptide complexes and identification of related HLAs potentially associated with long-term nonprogression.
حسب: Stewart-Jones, G, وآخرون
منشور في: (2005)

Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity
حسب: Mendoza, JL, وآخرون
منشور في: (2020)

Antigen-sensitive CD8 T-cell clones with tough HIV-1 suppression
حسب: Glanville, J, وآخرون
منشور في: (2013)

HIV-1 Env-specific cytotoxic T-lymphocyte responses in exposed, uninfected Kenyan sex workers: a prospective analysis.
حسب: Kaul, R, وآخرون
منشور في: (2004)

Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity
حسب: Mendoza, Juan L, وآخرون
منشور في: (2021)

Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity
حسب: Juan L Mendoza, وآخرون
منشور في: (2020-07-01)

Conservation of T cell receptor usage by HLA B27-restricted influenza-specific cytotoxic T lymphocytes suggests a general pattern for antigen-specific major histocompatibility complex class I-restricted responses.
حسب: Bowness, P, وآخرون
منشور في: (1993)

HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi.
حسب: Kaul, R, وآخرون
منشور في: (2000)

Importance of a conserved TCR J alpha-encoded tyrosine for T cell recognition of an HLA B27/peptide complex.
حسب: Bowness, P, وآخرون
منشور في: (1998)

Quantitative ex vivo analysis of functional virus-specific CD8 T lymphocytes in the blood and genital tract of HIV-infected women.
حسب: Kaul, R, وآخرون
منشور في: (2003)

HIV-1 and AIDS: what are protective immune responses?
حسب: Beattie, T, وآخرون
منشور في: (2002)

Broadly cross-reactive HIV-specific cytotoxic T-lymphocytes in highly-exposed persistently seronegative donors.
حسب: Rowland-Jones, S, وآخرون
منشور في: (1999)

Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi.
حسب: Rowland-Jones, S, وآخرون
منشور في: (1998)

Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses.
حسب: Kaul, R, وآخرون
منشور في: (2001)

Coreceptors and TCR Signaling – the Strong and the Weak of It
حسب: Alexander M. Mørch, وآخرون
منشور في: (2020-10-01)

The use of tetramers in the quantitative analysis of T-cell responses
حسب: Gillespie, G, وآخرون
منشور في: (2002)

Coreceptors and TCR signaling — the strong and the weak of it
حسب: Mørch, AM, وآخرون
منشور في: (2020)

A functional and structural basis for TCR cross-reactivity in multiple sclerosis.
حسب: Lang, H, وآخرون
منشور في: (2002)

An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity
حسب: Marcela V Maus, وآخرون
منشور في: (2016-01-01)

Recombination following superinfection by HIV-1.
حسب: Fang, G, وآخرون
منشور في: (2004)

Four novel cytotoxic T-lymphocyte epitopes in the highly conserved major homology region of HIV-1 Gag, restricted through B*4402, B*1801, A*2601, B*70 (B*1509)
حسب: Ogg, G, وآخرون
منشور في: (1998)

Characterization of two Epstein-Barr virus epitopes restricted by HLA-B7.
حسب: Hill, A, وآخرون
منشور في: (1995)

CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects.
حسب: Kaul, R, وآخرون
منشور في: (2001)

P17-28 LB. The antiviral efficacy of HIV-specific CD8+ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate
حسب: Rowland-Jones S, وآخرون
منشور في: (2009-10-01)

Identification of a tumor-specific allo-HLA–restricted γδTCR
حسب: G.J.J. Kierkels, وآخرون
منشور في: (2019-10-01)

An early HIV mutation within an HLA-B*57-restricted T cell epitope abrogates binding to the killer inhibitory receptor 3DL1.
حسب: Brackenridge, S, وآخرون
منشور في: (2011)

Cellular immune responses to HIV.
حسب: Mcmichael, A, وآخرون
منشور في: (2001)

HIV: Bad news for stop--start therapy?
حسب: Mcmichael, A, وآخرون
منشور في: (2002)

HIV type 1 resistance in Kenyan sex workers is not associated with altered cellular susceptibility to HIV type 1 infection or enhanced beta-chemokine production.
حسب: Fowke, K, وآخرون
منشور في: (1998)

An HLA-B35-restricted epitope modified at an anchor residue results in an antagonist peptide.
حسب: Dong, T, وآخرون
منشور في: (1996)