Antiparkinsonian efficacy of a novel transdermal delivery system for (+)-PHNO in MPTP-treated squirrel monkeys.

Antiparkinsonian efficacy of a novel transdermal delivery system for (+)-PHNO in MPTP-treated squirrel monkeys.

We examined the ability of the antiparkinsonian agent (+)-4-propyl-9-hydroxynaphthoxazine (PHNO) to enter the systemic circulation in therapeutic concentrations after continuous transdermal absorption in squirrel monkeys rendered parkinsonian by MPTP. Direct subcutaneous administration of (+)-PHNO i...

書目詳細資料
Main Authors:	Rupniak, N, Tye, S, Jennings, C, Loper, A, Bondi, J, Hichens, M, Hand, E, Iversen, S, Stahl, S
格式:	Journal article
語言:	English
出版:	1989

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