Progressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer.

RATIONALE: Amplification of distal 3q is the most common genomic aberration in squamous lung cancer (SQC). SQC develops in a multistage progression from normal bronchial epithelium through dysplasia to invasive disease. Identifying the key driver events in the early pathogenesis of SQC will facilita...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: McCaughan, F, Pole, J, Bankier, A, Konfortov, B, Carroll, B, Falzon, M, Rabbitts, T, George, P, Dear, P, Rabbitts, P
Μορφή: Journal article
Γλώσσα:English
Έκδοση: 2010