Progressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer.

RATIONALE: Amplification of distal 3q is the most common genomic aberration in squamous lung cancer (SQC). SQC develops in a multistage progression from normal bronchial epithelium through dysplasia to invasive disease. Identifying the key driver events in the early pathogenesis of SQC will facilita...

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Príomhchruthaitheoirí: McCaughan, F, Pole, J, Bankier, A, Konfortov, B, Carroll, B, Falzon, M, Rabbitts, T, George, P, Dear, P, Rabbitts, P
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2010