Progressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer.

RATIONALE: Amplification of distal 3q is the most common genomic aberration in squamous lung cancer (SQC). SQC develops in a multistage progression from normal bronchial epithelium through dysplasia to invasive disease. Identifying the key driver events in the early pathogenesis of SQC will facilita...

Description complète

Détails bibliographiques
Auteurs principaux: McCaughan, F, Pole, J, Bankier, A, Konfortov, B, Carroll, B, Falzon, M, Rabbitts, T, George, P, Dear, P, Rabbitts, P
Format: Journal article
Langue:English
Publié: 2010