Targeted neuronal nitric oxide synthase transgene delivery into stellate neurons reverses impaired intracellular calcium transients in prehypertensive rats

Hypertension is associated with the early onset of cardiac sympathetic hyperresponsiveness and enhanced intracellular Ca2+concentration [Ca2+]i in sympathetic neurons from both prehypertensive and hypertensive, spontaneously hypertensive rats (SHRs). Oxidative stress is a hallmark of hypertension, t...

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Hlavní autoři: Li, D, Nikiforova, N, Lu, C, Wannop, K, Mcmenamin, M, Lee, C, Buckler, K, Paterson, D
Médium: Journal article
Jazyk:English
Vydáno: 2013