Stereospecific alpha-methallylation of hydroxyaldehydes by silatropic ene cyclisation

Stereospecific alpha-methallylation of hydroxyaldehydes by silatropic ene cyclisation

We describe the thermal rearrangement of aldehydes bearing an α-(allyl- or crotylsilyl)oxy substituent. The transformations are best described mechanistically as intramolecular silatropic ene reactions based on stereoselectivity, kinetic and computed transition state data. The overall process consti...

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Autori principali:	Robertson, J, Hall, M, Green, S
Natura:	Journal article
Lingua:	English
Pubblicazione:	2009

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