Antibodies affecting ion channel function in acquired neuromyotonia, in seropositive and seronegative myasthenia gravis, and in antibody-mediated arthrogryposis multiplex congenita.

A new autoimmune disease affecting the neuromuscular junction has been defined. Acquired neuromyotonia is associated with antibodies to voltage-gated potassium channels that act, at least in part, by reducing potassium channel function with resulting neuronal hyperactivity. This condition is quite f...

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Hlavní autoři: Vincent, A, Jacobson, L, Plested, P, Polizzi, A, Tang, T, Riemersma, S, Newland, C, Ghorazian, S, Farrar, J, MacLennan, C, Willcox, N, Beeson, D, Newsom-Davis, J
Médium: Journal article
Jazyk:English
Vydáno: 1998