Functional analysis of POLE exonuclease domain mutations in cancer

Antzeko izenburuak

• Prognostic benefit of POLE exonuclease domain mutations in endometrial cancer cannot be explained by increased sensitivity to adjuvant treatment strategies
  nork: Van Gool, I, et al.
  Argitaratua: (2017)
• Somatic POLE exonuclease domain mutations elicit enhanced intratumoral immune responses in stage II colorectal cancer
  nork: Dan Huang, et al.
  Argitaratua: (2020-10-01)
• DNA polymerase ε and δ exonuclease domain mutations in endometrial cancer.
  nork: Church, D, et al.
  Argitaratua: (2013)
• Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neo-antigen burden and immune response
  nork: Temko, D, et al.
  Argitaratua: (2018)
• POLE and POLD1 germline exonuclease domain pathogenic variants, a rare event in colorectal cancer from the Middle East
  nork: Abdul K. Siraj, et al.
  Argitaratua: (2020-08-01)