Defining the impact of melanopsin missense polymorphisms using in vivo functional rescue

Melanopsin (OPN4) is an opsin photopigment expressed within intrinsically photosensitive retinal ganglion cells (ipRGCs) that mediate non-image forming (NIF) responses to light. Two single nucleotide polymorphisms (SNPs) in human melanopsin (hOPN4), Pro10Leu and Thr394Ile, have recently been associa...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Rodgers, J, Hughes, S, Pothecary, C, Brown, L, Hickey, D, Peirson, S, Hankins, M
स्वरूप: Journal article
भाषा:English
प्रकाशित: Oxford University Press 2018