Formation of complexes between self-peptides and MHC class II molecules in cells defective for presentation of exogenous protein antigens.
A vertebrate immune response is initiated by the presentation of foreign protein Ag to MHC class II-restricted T lymphocytes by specialized APC. Presentation of self-peptides in association with MHC class II molecules is also necessary for the induction of T cell tolerance. It is important to unders...
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| Format: | Journal article |
| Language: | English |
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1992
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