Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer

Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer

Observational studies have associated adiposity with an increased risk of colorectal cancer (CRC). However, such studies do not establish a causal relationship. To minimise bias from confounding we performed a Mendelian randomisation (MR) analysis to examine the relationship between adiposity and CR...

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Hlavní autoři: Jarvis, D, Mitchell, J, Law, P, Palin, K, Tuupanen, S, Gylfe, A, Hänninen, U, Cajuso, T, Tanskanen, T, Kondelin, J, Kaasinen, E, Sarin, A, Kaprio, J, Eriksson, J, Rissanen, H, Knekt, P, Pukkala, E, Jousilahti, P, Salomaa, V, Ripatti, S, Palotie, A, Järvinen, H, Renkonen-Sinisalo, L, Lepistö, A, Böhm, J, Meklin, J, Al-Tassan, N, Palles, C, Martin, L, Barclay, E, Farrington, S, Timofeeva, M, Meyer, B, Wakil, S, Campbell, H, Smith, C, Idziaszczyk, S, Maughan, T, Kaplan, R, Kerr, R, Kerr, D, Buchanan, D, Win, A, Hopper, J, Jenkins, M, Lindor, M, Newcomb, P, Gallinger, S, Conti, D, Schumacher, F, Casey, G, Taipale, J, Aaltonen, L, Cheadle, J, Dunlop, M, Tomlinson, I, Houlston, R
Médium: Journal article
Jazyk:English
Vydáno: Cancer Research UK 2016

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