Tolerance induction with CD4 monoclonal antibodies.

One of the major goals of therapeutic immunosuppression is to be able to use short-term therapy to achieve long-term tolerance. Short courses of CD4 antibodies are able to create peripheral tolerance in a mature immune system. The resulting tolerant state shows evidence of being dominant in that one...

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Bibliographic Details
Main Authors: Waldmann, H, Bemelman, F, Cobbold, S
Format: Journal article
Language:English
Published: 1998