Computational studies of talin-mediated integrin activation

<p>Integrins are large heterodimeric (αβ) cell surface receptors that play a key role in the formation of focal adhesion complexes and are involved in various signal transduction pathways. They are ‘activated’ to a high affinity state by the formation of an intracellular complex between the m...

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Bibliographic Details
Main Author: Kalli, A
Other Authors: Sansom, M
Format: Thesis
Language:English
Published: 2013
Subjects: