Vitamin K antagonists in heart disease: current status and perspectives (Section III). Position paper of the ESC Working Group on Thrombosis--Task Force on Anticoagulants in Heart Disease.

Vitamin K antagonists in heart disease: current status and perspectives (Section III). Position paper of the ESC Working Group on Thrombosis--Task Force on Anticoagulants in Heart Disease.

Oral anticoagulants are a mainstay of cardiovascular therapy, and for over 60 years vitamin K antagonists (VKAs) were the only available agents for long-term use. VKAs interfere with the cyclic inter-conversion of vitamin K and its 2,3 epoxide, thus inhibiting γ-carboxylation of glutamate residues a...

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Váldodahkkit: De Caterina, R, Husted, S, Wallentin, L, Andreotti, F, Arnesen, H, Bachmann, F, Baigent, C, Huber, K, Jespersen, J, Kristensen, S, Lip, G, Morais, J, Rasmussen, L, Siegbahn, A, Verheugt, F, Weitz, J
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: 2013

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