Evaluation of the efficacy of chad63-mva vectored vaccines expressing circumsporozoite protein and me-trap against controlled human malaria infection in malaria-naive individuals

<p style="text-align:justify;"> <b>Background:</b> Circumsporozoite protein (CS) is the antigenic target for RTS,S, the most advanced malaria vaccine to date. Heterologous prime-boost with the viral vectors simian adenovirus 63 (ChAd63)-modified vaccinia virus Ankara (MV...

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主要な著者: Hodgson, SH, Ewer, KJ, Bliss, CM, Edwards, NJ, Rampling, T, Anagnostou, NA, De Barra, E, Havelock, T, Bowyer, G, Poulton, ID, De Cassan, S, Longley, R, Illingworth, JJ, Douglas, AD, Mange, PB, Collins, KA, Roberts, R, Gerry, S, Berrie, E, Moyle, S, Colloca, S, Cortese, R, Sinden, RE, Gilbert, SC, Bejon, P, Lawrie, AM, Nicosia, A, Faust, SN, Hill, AV
フォーマット: Journal article
言語:English
出版事項: Oxford University Press 2014