Quantifying the underestimation of relative risks from genome-wide association studies

Genome-wide association studies (GWAS) have identified hundreds of associated loci across many common diseases. Most risk variants identified by GWAS will merely be tags for as-yet-unknown causal variants. It is therefore possible that identification of the causal variant, by fine mapping, will iden...

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Bibliografske podrobnosti
Main Authors: Spencer, C, Hechter, E, Vukcevic, D, Donnelly, P
Format: Journal article
Jezik:English
Izdano: Public Library of Science 2011
Teme: