The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection.
Identification of the transmitted/founder virus makes possible, for the first time, a genome-wide analysis of host immune responses against the infecting HIV-1 proteome. A complete dissection was made of the primary HIV-1-specific T cell response induced in three acutely infected patients. Cellular...
Main Authors: | Goonetilleke, N, Liu, M, Salazar-Gonzalez, J, Ferrari, G, Giorgi, E, Ganusov, V, Keele, B, Learn, G, Turnbull, E, Salazar, MG, Weinhold, K, Moore, S, Letvin, N, Haynes, B, Cohen, MS, Hraber, P, Bhattacharya, T, Borrow, P, Perelson, A, Hahn, B, Shaw, G, Korber, B, Mcmichael, A |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2009
|
Similar Items
-
Quantifying factors determining the rate of CTL escape and reversion during acute and chronic phases of HIV infection
by: Ganusov, V, et al.
Published: (2010) -
Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infection.
by: Ganusov, V, et al.
Published: (2011) -
Reversion and T cell escape mutations compensate the fitness loss of a CD8+ T cell escape mutant in their cognate transmitted/founder virus.
by: Song, H, et al.
Published: (2014) -
The Role of T Cell Immunity in the Control of HIV Infection
by: Goonetilleke, N, et al.
Published: (2010) -
Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing.
by: Fischer, W, et al.
Published: (2010)