HLA analysis of Sri Lankan Sinhalese predicts North Indian origin.

The origin of the Sinhalese population of Sri Lanka is debated. We subtyped HLA-A*02 in 101 Sinhalese and observed a preponderance of the rare allele HLA-A*0211 which was similar to reported frequencies in northern India. Taken with low-resolution typing for the remaining A, B, C, DR and DQ alleles,...

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Bibliografiska uppgifter
Huvudupphovsmän: Malavige, G, Rostron, T, Seneviratne, S, Fernando, S, Sivayogan, S, Wijewickrama, A, Ogg, G
Materialtyp: Journal article
Språk:English
Publicerad: 2007
Beskrivning
Sammanfattning:The origin of the Sinhalese population of Sri Lanka is debated. We subtyped HLA-A*02 in 101 Sinhalese and observed a preponderance of the rare allele HLA-A*0211 which was similar to reported frequencies in northern India. Taken with low-resolution typing for the remaining A, B, C, DR and DQ alleles, these data suggest a North Indian origin for the Sri Lankan Sinhalese.