Assessment of the value of therapeutic monitoring of tacrine in Alzheimer's disease.
OBJECTIVES: The purpose of this study was to validate the lower end of the putative therapeutic range of serum tacrine concentrations of 7-20 ng ml(-1) in the treatment of Alzheimer's disease. METHODS: The relationship between dose, steady-state serum tacrine concentrations and change in MMSE s...
Main Authors: | Roberts, C, Ford, J, Truman, C, Scott, M, Mäkelä, P, Wilcock, G |
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Format: | Journal article |
Language: | English |
Published: |
1998
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