The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation
Polychlorinated aromatic compounds are persistent environmental contaminants; we describe here the redesign and engineering of the haem monooxygenase cytochrome P450(cam) to oxidise these compounds efficiently to the chlorinated phenols which are readily degraded by many micro-organisms, thus provid...
المؤلفون الرئيسيون: | , , |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2000
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_version_ | 1826303622935216128 |
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author | Jones, J O'Hare, E Wong, L |
author_facet | Jones, J O'Hare, E Wong, L |
author_sort | Jones, J |
collection | OXFORD |
description | Polychlorinated aromatic compounds are persistent environmental contaminants; we describe here the redesign and engineering of the haem monooxygenase cytochrome P450(cam) to oxidise these compounds efficiently to the chlorinated phenols which are readily degraded by many micro-organisms, thus providing a basis for novel systems for biological clean-up of these inert compounds. |
first_indexed | 2024-03-07T06:05:31Z |
format | Journal article |
id | oxford-uuid:edb48e3c-8c5b-4f6b-a844-5da2c7a28c5c |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T06:05:31Z |
publishDate | 2000 |
record_format | dspace |
spelling | oxford-uuid:edb48e3c-8c5b-4f6b-a844-5da2c7a28c5c2022-03-27T11:27:03ZThe oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediationJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:edb48e3c-8c5b-4f6b-a844-5da2c7a28c5cEnglishSymplectic Elements at Oxford2000Jones, JO'Hare, EWong, LPolychlorinated aromatic compounds are persistent environmental contaminants; we describe here the redesign and engineering of the haem monooxygenase cytochrome P450(cam) to oxidise these compounds efficiently to the chlorinated phenols which are readily degraded by many micro-organisms, thus providing a basis for novel systems for biological clean-up of these inert compounds. |
spellingShingle | Jones, J O'Hare, E Wong, L The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation |
title | The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation |
title_full | The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation |
title_fullStr | The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation |
title_full_unstemmed | The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation |
title_short | The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation |
title_sort | oxidation of polychlorinated benzenes by genetically engineered cytochrome p450 cam potential applications in bioremediation |
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