The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation

Polychlorinated aromatic compounds are persistent environmental contaminants; we describe here the redesign and engineering of the haem monooxygenase cytochrome P450(cam) to oxidise these compounds efficiently to the chlorinated phenols which are readily degraded by many micro-organisms, thus provid...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Jones, J, O'Hare, E, Wong, L
التنسيق: Journal article
اللغة:English
منشور في: 2000
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author Jones, J
O'Hare, E
Wong, L
author_facet Jones, J
O'Hare, E
Wong, L
author_sort Jones, J
collection OXFORD
description Polychlorinated aromatic compounds are persistent environmental contaminants; we describe here the redesign and engineering of the haem monooxygenase cytochrome P450(cam) to oxidise these compounds efficiently to the chlorinated phenols which are readily degraded by many micro-organisms, thus providing a basis for novel systems for biological clean-up of these inert compounds.
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spelling oxford-uuid:edb48e3c-8c5b-4f6b-a844-5da2c7a28c5c2022-03-27T11:27:03ZThe oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediationJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:edb48e3c-8c5b-4f6b-a844-5da2c7a28c5cEnglishSymplectic Elements at Oxford2000Jones, JO'Hare, EWong, LPolychlorinated aromatic compounds are persistent environmental contaminants; we describe here the redesign and engineering of the haem monooxygenase cytochrome P450(cam) to oxidise these compounds efficiently to the chlorinated phenols which are readily degraded by many micro-organisms, thus providing a basis for novel systems for biological clean-up of these inert compounds.
spellingShingle Jones, J
O'Hare, E
Wong, L
The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation
title The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation
title_full The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation
title_fullStr The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation
title_full_unstemmed The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation
title_short The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation
title_sort oxidation of polychlorinated benzenes by genetically engineered cytochrome p450 cam potential applications in bioremediation
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