The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation

The oxidation of polychlorinated benzenes by genetically engineered cytochrome P450(cam): potential applications in bioremediation

Polychlorinated aromatic compounds are persistent environmental contaminants; we describe here the redesign and engineering of the haem monooxygenase cytochrome P450(cam) to oxidise these compounds efficiently to the chlorinated phenols which are readily degraded by many micro-organisms, thus provid...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Jones, J, O'Hare, E, Wong, L
Natura:	Journal article
Lingua:	English
Pubblicazione:	2000

Documenti analoghi

Oxidation of polychlorinated benzenes by genetically engineered CYP101 (cytochrome P450(cam)).
di: Jones, J, et al.
Pubblicazione: (2001)

Engineering cytochrome P450s for bioremediation /
di: 242771 Kellner, David G., et al.

Butane and propane oxidation by engineered cytochrome P450cam.
di: Bell, S, et al.
Pubblicazione: (2002)

Butane and propane oxidation by engineered cytochrome P450cam.
di: Bell, S, et al.
Pubblicazione: (2002)

Protein engineering of cytochrome P450(cam)
di: Wong, L, et al.
Pubblicazione: (1997)

Engineering the haem monooxygenase cytochrome P450(cam) for monoterpene oxidation
di: Bell, S, et al.
Pubblicazione: (2001)

Engineering cytochrome P450cam into an alkane hydroxylase
di: Bell, S, et al.
Pubblicazione: (2003)

The oxidation of naphthalene and pyrene by cytochrome P450cam.
di: England, P, et al.
Pubblicazione: (1998)

Engineering molecular recognition in alkane oxidation catalysed by cytochrome P450(cam)
di: Stevenson, J, et al.
Pubblicazione: (1998)

Structure-activity correlations in pentachlorobenzene oxidation by engineered cytochrome P450cam.
di: Xu, F, et al.
Pubblicazione: (2007)

Engineering the selectivity of aliphatic C-H bond oxidation catalysed by cytochrome P450cam
di: Jones, N, et al.
Pubblicazione: (1996)

Engineering substrate recognition in catalysis by cytochrome P450cam.
di: Bell, S, et al.
Pubblicazione: (2003)

The heme monooxygenase cytochrome P450cam can be engineered to oxidize ethane to ethanol.
di: Xu, F, et al.
Pubblicazione: (2005)

Direct electrochemistry of cytochrome P450cam
di: Kazlauskaite, J, et al.
Pubblicazione: (1996)

The Bacterial Cytochrome P450 Monooxygenases: P450cam and P450BM-3
di: Urlacher, V, et al.
Pubblicazione: (2007)

The catalytic oxidation of linear and branched alkanes by cytochrome P450(cam)
di: Stevenson, J, et al.
Pubblicazione: (1996)

Molecular recognition in (+)-alpha-pinene oxidation by cytochrome P450cam.
di: Bell, S, et al.
Pubblicazione: (2003)

Protein engineering of cytochrome p450(cam) (CYP101) for the oxidation of polycyclic aromatic hydrocarbons.
di: Harford-Cross, C, et al.
Pubblicazione: (2000)

Biotransformation of the sesquiterpene (+)-valencene by cytochrome P450cam and P450BM-3.
di: Sowden, R, et al.
Pubblicazione: (2005)

Reductive Cytochrome P450 Reactions and Their Potential Role in Bioremediation
di: James B. Y. H. Behrendorff, et al.
Pubblicazione: (2021-04-01)

A scanning tunnelling study of immobilised cytochrome P450cam.
di: Davis, J, et al.
Pubblicazione: (2000)

The dimerization of Pseudomonas putida cytochrome P450cam: practical consequences and engineering of a monomeric enzyme.
di: Nickerson, D, et al.
Pubblicazione: (1997)

The thermodynamics and kinetics of electron transfer in the cytochrome P450cam enzyme system.
di: Honeychurch, M, et al.
Pubblicazione: (1999)

Surface-modified mutants of cytochrome P450cam: enzymatic properties and electrochemistry.
di: Lo, K, et al.
Pubblicazione: (1999)

The catalytic activity of cytochrome P450cam towards styrene oxidation is increased by site-specific mutagenesis.
di: Nickerson, D, et al.
Pubblicazione: (1997)

Design and engineering of cytochrome P450 systems
di: Bell, S, et al.
Pubblicazione: (2007)

Thermodynamics of camphor migration in cytochrome P450cam by atomistic simulations
di: J. Rydzewski, et al.
Pubblicazione: (2017-08-01)

Mutations of phenylalanine-193 in the putative substrate access channel alter the substrate specificity of cytochrome P450(cam)
di: Stevenson, J, et al.
Pubblicazione: (2000)

Cytochrome P450 monooxygenases.
di: Wong, L
Pubblicazione: (1998)

An improved procedure for the preparation of X-ray diffraction-quality crystals of cytochrome p450cam.
di: Nickerson, D, et al.
Pubblicazione: (1998)

Mutations of glutamate-84 at the putative potassium-binding site affect camphor binding and oxidation by cytochrome p450cam.
di: Westlake, A, et al.
Pubblicazione: (1999)

The use of active site mutants of cytochrome P450(cam) in chemical synthesis
di: Bell, S, et al.
Pubblicazione: (1999)

Catalytic reductive dehalogenation of hexachloroethane by molecular variants of cytochrome P450cam (CYP101).
di: Walsh, M, et al.
Pubblicazione: (2000)

CYTOCHROME P-450(CAM) MONOOXYGENASE CAN BE REDESIGNED TO CATALYZE THE REGIOSELECTIVE AROMATIC HYDROXYLATION OF DIPHENYLMETHANE
di: Fowler, S, et al.
Pubblicazione: (1994)

Selective aliphatic and aromatic carbon-hydrogen bond activation catalysed by mutants of cytochrome P450(cam)
di: Bell, S, et al.
Pubblicazione: (1997)

Partial fusion of a cytochrome P450 system by carboxy-terminal attachment of putidaredoxin reductase to P450cam (CYP101A1)
di: Johnson, E, et al.
Pubblicazione: (2016)

Putidaredoxin binds to the same site on cytochrome P450cam in the open and closed conformation
di: Liou, S, et al.
Pubblicazione: (2017)

Hydroxylation of anilides by engineered cytochrome P450BM3
di: O'Hanlon, J, et al.
Pubblicazione: (2017)

Aliphatic vs aromatic C-H bond activation of phenylcyclohexane catalysed by cytochrome P450cam
di: England, P, et al.
Pubblicazione: (1996)

Suppression of Peroxisomal Enzyme Activities and Cytochrome P450 4A Isozyme Expression by Congeneric Polybrominated and Polychlorinated Biphenyls
di: Larry W. Robertson, et al.
Pubblicazione: (2007-01-01)